The identification of genes predisposing to human diseases is of paramount importance for understanding the molecular basis of the disease and individually different drug response, and will establish new routes to diagnosis and therapeutic advances of immense medical benefit.

A key step in all strategies for disease gene identification is the resequencing of candidate genes or other genomic regions of interest in patients and controls to identify those single nucleotide polymorphisms (SNPs) associated with a certain phenotype.

We therefore have implemented a technology service platform for candidate gene sequence analysis, that integrates high throughput (HT) resequencing and bioinformatic techniques.

The need for such a service infrastructure has already been expressed by a number of researchers with a strong interest in candidate gene sequencing from the various clinical networks.

Costs for comparative candidate gene sequencing are highly depending on the gene specific exon / intron structure, template quality, completeness of the data set, etc. and can be calculated on an individual basis only.

The coordination of the various sequencing requests from the network partners will be performed through our web interface on this site.